Cenforce 150 mg

How Cenforce 150mg works

The active ingredient in Cenforce 150 mg Tablet is sildenafil citrate. It inhibits the enzyme phosphodiesterase type 5 (PDE-5). PDE-5 is the substance that breaks down cGMP, a substance that helps with erections. By inhibiting PDE-5, sildenafil raises the level of cGMP. This results in the relaxation of smooth muscle cells, increasing blood flow.

In erectile dysfunction, this mechanism helps to get a hard erection. In pulmonary arterial hypertension, it reduces resistance to blood flow i.e., in the pulmonary artery. Thus, it helps lower pulmonary arterial pressure.

Cenforce 150 mg will not take effect if the man is not sexually aroused. Sexual stimulation (physical touch etc.) is necessary for the drug to work.

Uses of Cenforce 150mg

• Erectile dysfunction

Trouble achieving or sustaining an erection hard enough for sex.

Benefits

• Improves erection quality, and chances of successful intercourse in men with ED,
• Builds sexual confidence,
• Increases self-esteem,
• Improves quality of life and relationships

Recommended Dosage

Talk to a physician about a suitable dosage for you. The doses for ED are 50 mg and 100 mg. In severe cases where low doses do not work, the doctor may prescribe Cenforce 150. Your dose depends on other factors, e.g., any other health condition you might have/ other medications that you take.

Take the tablet about 30-45 minutes before sexual intercourse, with a light snack. Avoid fatty food as it will prevent the drug from working quickly. Do not wait for too long (4-6 hours) after taking the tablet to have sex.

Missed Dosage

If you have forgotten to take a scheduled dose, take it as soon as you remember. If the time for your next dose is near (less than 12 hours remain), skip the missed dose. Taking the two doses within 12 hours may lead to an overdose.

Overdose

Overdosing on an ED medication can cause serious problems. It will intensify the side effects of the drug. This may include vomiting, blurred vision, vertigo, and priapism. Priapism is a painful long erection lasting for >4 hours. Avoid overdosing on this medication at all costs. If you suspect an overdose, get emergency medical attention.

Safety Advice

Alcohol : UNSAFE
It is unsafe to drink alcohol with Cenforce 150mg (sildenafil) Tablets.

Pregnancy : POSSIBLY UNSAFE
This medicine is not approved for use in women. It’s for male sexual health problems (impotence or ED).

Breastfeeding :  POSSIBLY UNSAFE
This medicine is not meant for women’s use. Information regarding the use of Cenforce 150mg Pills during pregnancy or breastfeeding is not available. Consult your doctor for further information.

Driving : UNSAFE
This drug can make you dizzy or affect your vision. Do not drive or use hazardous machinery until you are fully aware of its effects on you.

Kidney : POSSIBLY SAFE
Sildenafil is not known to impair kidney health. Use caution if you have severe kidney disease. Consult your doctor before taking this medicine.

Liver:  CAUTION
Cenforce will be processed by your liver, so use caution if you have an existing liver problem. Consult your doctor for further advice. Your doctor will probably adjust the dosage for you. 

Other Precautions

People with certain health conditions should avoid taking Cenforce tablets. To avoid any adverse effects, tell your doctor about your medical history. Get a full body check-up before taking this medicine. Let your doctor know:

• If you’ve had an allergic reaction to sildenafil citrate.
• If you suffer from a heart condition, e.g., aortic stenosis and hypertrophic obstructive cardiomyopathy  
• If you suffer from Pulmonary Veno-occlusive disease (PVOD)
• If you have suffered a heart attack or angina attack before
• If your blood doesn’t coagulate quickly. Or, you have a blood-related disorder like sickle-cell anemia 
• If you take medicine to treat high blood pressure
• If you are partially or fully blind
• If your kidney and/or liver do not function normally
• If you have a deformed penis. It may be due to conditions like Peyronie’s disease or cavernosal fibrosis
• If you take blood pressure medications
• If you’ve had epileptic seizures in the past
• If you have (or had) an ulcer 
• If your doctor has advised you against having sex for some reason

Women and children must not consume Cenforce 150 mg.

Side effects of Cenforce 150mg

Side effects of Cenforce 150 mg

Sildenafil citrate is a well-tolerated drug. It can still have some side effects like

• Nausea
• Dizziness
• Stomach upset 
• Back pain
• Tingling sensation/ flushing
• Stuffy nose
• Sleep problems
• Common cold-like symptoms, e.g., runny nose 

The above side effects are common but should go away on their own. 

Some serious side effects are:

• Chest pain
• Rashes/ hives
• Vomiting
• Pain extending from your jaw to the shoulders
• Intense back pain and muscle pain
• Priapism
• Low blood pressure
• Sudden vision loss, aka non-arteritic anterior ischaemic optic neuropathy (NAION)
• A ringing sensation in the ears
• Cough with mucus
• Palpitations
• Swelling in tongue, throat, hands, legs. Etc.
• Convulsions
• Sweating

If any of these symptoms appear in the patient, contact a doctor immediately.

Drugs Interactions

Some drugs can interact with Cenforce 150mg. This increases the risk of having side effects. This can also reduce the medicine’s efficacy.  Tell your doctor about all the prescription drugs and OTC medicines you are taking. Also, discuss the herbs or supplements you might be taking. Here is a list of possible drug interactions:

• Nitrate based medications
• CYP3A4 Inhibitors such as ketoconazole, itraconazole, saquinavir, etc
• Calcium channel blockers such as amlodipine
• Guanylate cyclase (GC) stimulators like Riociguat 
• Alpha-blockers such as prazosin, doxazosin, terazosin, etc
• Beta-blockers such as betaxolol, atenolol, etc
• Certain antibiotics, such as erythromycin and clarithromycin
• Mifepristone aka RU-486
• HIV protease inhibitors such as fosamprenavir
• Hepatitis C virus protease inhibitors such as telaprevir, boceprevir, etc
• Medications used to treat epilepsy, like carbamazepine
• Rifampin
• Other ED medications like Cialis, Levitra, etc
• Efavirenz

Stop taking the medicine and get medical assistance if any side effects bother you.

Interaction with alcohol

It is better not to consume large amounts of alcohol with Cenforce 150mg. The combination can lower your blood pressure suddenly, making you dizzy. It may also intensify the other side effects of this drug.

Interaction with grapefruit juice

Avoid grapes/grape juice while on this medication. It can interact with sildenafil citra

Storage Instructions

• Store the Cenforce 150mg tablets in their original packaging. 
• Keep them at room temperature (about 59–86° F or 15–30° C). 
• Store them away from direct sunlight, moisture, and dampness.
• Do not consume the pills if they’ve crossed the expiry date.
• Store them at a safe distance from children and pets.
• Proper disposal of empty packets and expired pills is necessary

References

1. Fink, H. A., Mac Donald, R., Rutks, I. R., Nelson, D. B., & Wilt, T. J. (2002b). Sildenafil for male erectile dysfunction. Archives of Internal Medicine, 162(12), 1349. https://doi.org/10.1001/archinte.162.12.1349
2. Smith, B. P., & Babos, M. (2023, February 14). Sildenafil. StatPearls – NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK558978/
3. Galiè, N., Ghofrani, H. A., Torbicki, A., Barst, R. J., Rubin, L. J., Badesch, D., Fleming, T., Parpia, T., Burgess, G., Branzi, A., Grimminger, F., Kurzyna, M., & Simonneau, G. (2005). Sildenafil citrate therapy for pulmonary arterial hypertension. New England Journal of Medicine, 353(20), 2148–2157. https://doi.org/10.1056/nejmoa050010
4. Sofikitis, N., Kaltsas, A., Dimitriadis, F., Rassweiler, J., Grivas, N., Zachariou, A., Kaponis, A., Tsounapi, P., Paterakis, N., Karagiannis, A., Skouros, S., Giannakis, I., Champilomatis, I., Paschopoulos, M., Daphnis, D., Giakoumakis, I., R Gabales, M., Chua, J. B. M., Lantin, P. L., III, . . . Takenaka, A. (2021). The effect of PDE5 inhibitors on the male reproductive tract. Current Pharmaceutical Design, 27(23), 2697–2713. https://doi.org/10.2174/1381612826666200226121510
5. Kim, J. N., Oh, J. J., Park, D. S., Hong, Y. K., & Yu, Y. D. (2019). Influence of Alcohol on Phosphodiesterase 5 inhibitors Use in Middle- to Old-Aged Men: A Comparative Study of Adverse Events. Sexual Medicine, 7(4), 425–432. https://doi.org/10.1016/j.esxm.2019.07.004