Active Ingredient | Dapoxetine |
Starts In | 1 to 3 hours |
Last Long | Up to 4 hours |
Type | Premature Ejaculation |
Manufacturer | Sunrise Remedies Pvt. Ltd. |
How It Works
Dapoxetine works by increasing the activity of Serotonin in the brain. It is a short-acting, Selective Serotonin Reuptake Inhibitor (SSRI) that blocks the reabsorption of Serotonin into neurons. This makes it possible for Serotonin to be made available to the brain. Thus, the transmission of messages between neurons is improved. The process of ejaculation gets delayed by a few minutes. This helps the person to have satisfying sexual intercourse with his partner by gaining control over his ejaculation.
Uses
The tablet is prescribed for the treatment of the following conditions:
- Premature Ejaculation (PE) – a condition that causes a man to ejaculate sooner than he or his partner would expect him to during sexual intercourse.
Dosage
Dapoxetine comes in the following dosage:
- 30 mg
- 60 mg
- 90 mg
This tablet is meant to be taken orally with water. It can be taken with or without food. For best results, it is recommended to take the pill 1 to 3 hours before sexual intercourse. Do not consume more than one tablet in 24 hours.
Follow your doctor’s prescription carefully and read all the instructions mentioned on the pack of the drug.
Missed Dosage: This medicine is taken as and when needed. Therefore, you are unlikely to miss a dose.
Overdose: An overdose of the drug can lead to various side effects. If an overdose is suspected, seek medical help immediately.
Important Advisory
Before you take Dapoxetine tablets, tell your doctor:
- If you suffer from epilepsy.
- If you have a history of heart attack, stroke, or congestive heart failure.
- If you suffer from problems such as diabetes, hypertension, angina, etc.
- If you have kidney or liver problems.
- If you have a history of fainting.
- If you have a bleeding disorder such as hemophilia.
- If you suffer from anxiety and depression.
- If you have a history of uncontrolled blood pressure.
Dapoxetine Side Effects
Common side effects include:
- Headaches
- Nausea
- Dizziness
- Diarrhea
- Dry mouth
- Insomnia
- Upset stomach
- Flushing
- Excessive sweating
- Blurred vision
- Tiredness
- Increased blood pressure
Drug Interactions
Certain drugs are known to interact with Dapoxetine and affect the way it works. If you take any herbal, OTC, recreational, or any other form of drugs, let your doctor know about them.
- Antibiotics such as Erythromycin
- Fluconazole
- Ketoconazole
- Duloxetine
- Linezolid
- Lithium
- Monoamine Oxidase Inhibitors (MAOIs) such as phenelzine, tranylcypromine
- Rasagiline
- Selegiline
- Tramadol
- Warfarin
- Ritonavir
- Tryptophan
- Verapamil
- Antidepressants such as Paroxetine and Fluoxetine
Interaction with alcohol
Alcohol can increase the risk of experiencing side effects. Avoid consuming alcohol along with this medicine.
Storage Instructions
Dapoxetine tablets are meant to be stored properly and safely in their original packaging.
- Keep the pills out of reach of children.
- Keep the pills away from direct heat, moisture, and sunlight.
- Once the pack is opened, store the pill in an airtight container.
- Do not consume the pills past their expiration date.
Substitutes Available
Frequent Asked Questions (FAQ)
How long does Dapoxetine make you last?
Ans. The initial half-life of Dapoxetine is around 1.4 hours. It has a terminal half-life of 18.7 hours for the 30 mg dose and 21.9 hours for the 60 mg dose. It is, therefore, recommended to take this pill 1 to 3 hours before sexual intercourse.
Is it safe to take Dapoxetine?
Ans. Dapoxetine is considered safe and effective for the treatment of Premature Ejaculation (PE).
Can you take Dapoxetine with Viagra?
Ans. According to a study conducted on 74 patients suffering from lifelong or acquired PE and ED, 81.13% of patients who received a combination of Sildenafil and Dapoxetine were satisfied with the treatment.
Can I take Dapoxetine daily?
Ans. Dapoxetine is recommended to be taken once in 24 hours. This pill is taken as and when needed. Therefore, this pill shouldn’t be taken daily unless the person indulges in any sexual activity frequently.
How quickly does Dapoxetine work?
Ans. The peak plasma levels of Dapoxetine are reached in approximately 1 hour following a dose of 30 mg or 60 mg.
References
- [Internet]. 2022 [cited 2022 Sep 27]. Available from: https://www.netdoctor.co.uk/medicines/sexual/a8807/priligy-dapoxetine/
- McMahon CG. Dapoxetine: a new option in the medical management of premature ejaculation. Ther Adv Urol. 2012 Oct;4(5):233-51. doi: 10.1177/1756287212453866. PMID: 23024705; PMCID: PMC3441133. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441133/
- McMahon CG. Efficacy of dapoxetine in the treatment of premature ejaculation. Clin Med Insights Reprod Health. 2011 Aug 2;5:25-39. doi: 10.4137/CMRH.S7337. PMID: 24453509; PMCID: PMC3888071. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888071/
- McCarty E, Dinsmore W. Dapoxetine: an evidence-based review of its effectiveness in treatment of premature ejaculation. Core Evid. 2012;7:1-14. doi: 10.2147/CE.S13841. Epub 2012 Jan 19. PMID: 22315582; PMCID: PMC3273363. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273363/
- Roushar A. Dapoxetine for Premature Ejaculation Has High Discontinuation Rate [Internet]. ISSM. 2022 [cited 2022 Sep 27]. Available from: https://www.issm.info/sexual-health-headlines/dapoxetine-for-premature-ejaculation-has-high-discontinuation-rate
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Tuken, M., Culha, M.G. & Serefoglu, E.C. Efficacy and safety of dapoxetine/sildenafil combination tablets in the treatment of men with premature ejaculation and concomitant erectile dysfunction—DAP-SPEED Study. Int J Impot Res 31, 92–96 (2019). Available from: https://www.nature.com/articles/s41443-019-0122-2
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