How does Cenforce 120 mg work
The medication contains the active ingredient Sildenafil Citrate, a medicine from the PDE5 inhibitor group. The medication blocks the enzyme that breaks down cGMP, allowing blood vessels in the penis to relax and increase blood flow. This helps maintain a firmer and longer-lasting erection during sexual arousal.
During sexual stimulation, the blood vessel lining in the penis releases nitric oxide (NO), which triggers the production of cGMP in the smooth muscle cells of the penis. cGMP prompts the smooth muscle cells to relax. This action widens the penis’ blood vessels. The relaxation of smooth muscle cells allows for improved blood flow into the spongy tissue of the penis. This tissue is called the corpus cavernosum. The increased blood flow fills the spongy tissue, leading to an erection.
These pills do not directly induce an erection. Instead, it enhances the natural erectile response by amplifying penile blood flow upon sexual stimulation.
Uses of Cenforce 120 mg
Cenforce 120 mg is a potent drug to treat erectile dysfunction problems. It helps improve blood flow to the penis, allowing men to achieve and maintain an erection during sexual activity. Cenforce is taken when sexual stimulation is expected, as it works only in response to sexual arousal.
Recommended Dosage
Take one tablet about 30 minutes to 1 hour before sexual activity. This pill is recommended to be taken once in 24 hours. The effects of this medicine last for around 4 to 6 hours. We recommend you to not alter the dose without consulting a physician as lower dose can be ineffective and overdose can lead to side effects. The medicine is better taken on an empty stomach as a heavy meal can slow down its onset time.
Missed Dosage
This pill is taken as and when needed. Therefore, the chances of missing a dose are very less. If it’s time for your next scheduled dose, skip the missed dose. Consult your doctor about what should be done when a dose is missed.
Overdose
Overdosing on any drug can have consequences. Cenforce 120 mg, if taken in excessive amounts can result in headache, swelling of body parts, breathing problems, a more than four hour long painful erection (priapism), etc. To avoid such severe symptoms, you must avoid overdosing on this medicine. If you or someone you know is showing these symptoms, call a doctor instantly and get help.
Important Advisory
As with any medication, you should inform your doctor about all the health conditions you suffer or have suffered from. This will help them decide whether or not to prescribe sildenafil. Here are some health conditions that should be considered carefully before taking Cenforce 120 mg:
- Any allergic reaction to sildenafil or any other content of drug in the past
- Partial or complete blindness
- Abnormal vision or any eye condition like retinitis pigmentosa
- High or low blood pressure conditions
- Bleeding problems like hemophilia
- Blood-related issues like leukemia or sickle-cell anemia
- Pulmonary Veno-occlusive disease (PVOD)
- Cardiovascular disorders like aortic stenosis, hypertrophic obstructive cardiomyopathy
- Ischemic heart condition or a history of angina attack/ heart attack
- Anatomical deformation of the penis as in the Peyronie’s disease or angulation or cavernosal fibrosis
- Any renal or hepatic condition
- Epilepsy or seizures
- Any condition that renders sexual activity inadvisable
- Peptic ulcer (both active and if you have had it in the past)
Additionally, Cenforce 120 mg is not directed for use by women or minors. Its effect on pregnant and breastfeeding ladies is also less known.
Side effects of Cenforce 120 mg
Despite being a well-tolerated medicine, Cenforce 120 mg can have side effects. It may be a result of an allergic reaction or a hypersensitive body or an overdose. Following are some common symptoms that should vanish after a while-
- Dizziness
- Nausea
- Diarrhea
- Heartburn
- Runny nose or stuffy nose
- Insomnia
- Flushing
Some more serious symptoms that can manifest mostly because of an allergy or overdose are-
- Swelling of body parts (tongue, face, throat, etc.)
- Rashes or hives
- Trouble in breathing
- Chest pain
- Abnormal heart rhythm
- Priapism
- Sudden vision loss (non-arteritic anterior ischaemic optic neuropathy (NAION))
- Visual color distortions
- Vertigo or a ringing sensation in the ears
- Vomiting
- Myalgia
- Penile hemorrhage
If you experience any severe or persistent side effects or notice any changes in your health, consult your doctor immediately.
Interaction With Other Drugs
Drug interaction increases the risk of having side effects, it may also reduce the efficacy of the drug. Cenforce 120 mg may interact with some drugs so you should tell your doctor about all the prescribed and OTC medicine you take. Also, let them know about the herbs and other dietary supplements like vitamin tablets you might be taking. Possible drug interactions include but are not limited to
- Medicines containing nitrates, like isosorbide and nitroglycerine (used for treating heart conditions like angina)
- Riociguat and the other Guanylate cyclase (GC) stimulators
- Viagra, Cialis, Levitra, and other PDE-5 inhibitors
- Amyl nitrite, amyl/ butyl nitrate, and other recreational drugs called ‘Poppers’
- Rifampin
- Efavirenz
- Clarithromycin, erythromycin, and other macrolide antibiotics
- Carbamazepine and other anti-seizure medications
- Alfuzosin, doxazosin, and other alpha-blockers
- Atenolol and other beta-blockers
- Fosamprenavir, saquinavir, and other HIV protease inhibitors
- Telaprevir, boceprevir, and other hepatitis C virus protease inhibitors
- Mifepristone, aka RU-486 (one of the 2 pills that form an MTP kit for abortion)
Interaction With Alcohol
Avoid consuming alcohol with Cenforce 120 mg as it may cause low blood pressure and, hence dizziness. The combination might also increase the risk of facing other side effects.
Interaction with grapefruit juice
Grapefruit juice raises the levels of this drug in the body and delays the time it takes for the medication to work. Therefore, it should not be consumed while taking this medication.
Storage Instructions
Follow these storage guidelines to keep the pills effective and intact for a longer time-
- Keep the tablets in their original packaging when not in use
- Keep them away from damp and direct sunlight (bathroom cabinet is not a suitable place)
- The place should be in the normal room temperature range, i.e., 59–86° F or 15–30° C
- Keep them beyond the reach of children and pets
- Do not consume past the expiry date
- Dispose of the discarded pills and empty packaging in a suitable manner, do not flush
Frequently Asked Questions (FAQs)
Q1. Does Cenforce 120 mg help improve sex life?
Ans- If you are suffering from erectile dysfunction and cannot gain or maintain a satisfactory erection during sex, Cenforce 120 mg can help you. It will improve blood flow into the penis and cause a rigid erection. However, it won’t increase your stamina or enhance your libido.
Q2. Who should not take Cenforce 120 mg?
Ans- Anyone not suffering from impotence must not take this medicine. Also, anyone suffering from heart, liver, kidney, and blood-related disorders should check with a physician before starting treatment with this medication. Lastly, women and children are not supposed to consume this medicine.
Q3. Is Cenforce 120 mg safe?
Ans- It is a moderately high dose of this medicine and though it is fairly well-tolerated, one should not overdose on it. The resulting side effects can range from nausea, headache, and lightheadedness, to priapism, vision loss, and chest pain. Talk to your doctor to know if it is safe for you.
Q4. How does Cenforce 120 mg work?
Ans- This drug works like all other PDE-5 inhibiting drugs (like Viagra and Levitra) by relaxing the penile muscles and enhancing blood flow in the penis. The result is a firmer erection that helps you have satisfactory sex.
References
- Fink HA, Mac Donald R, Rutks IR, Nelson DB, Wilt TJ. Sildenafil for male erectile dysfunction: a systematic review and meta-analysis. Arch Intern Med. 2002 Jun 24;162(12):1349-60. doi: 10.1001/archinte.162.12.1349. PMID: 12076233. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/211714
- Loran OB, Ströberg P, Lee SW, Park NC, Kim SW, Tseng LJ, Collins S, Stecher VJ. Sildenafil citrate 100 mg starting dose in men with erectile dysfunction in an international, double-blind, placebo-controlled study: effect on the sexual experience and reducing feelings of anxiety about the next intercourse attempt. J Sex Med. 2009 Oct;6(10):2826-35. doi: 10.1111/j.1743-6109.2009.01428.x. PMID: 19817982. https://www.jsm.jsexmed.org/article/S1743-6095(15)32273-6/fulltext
- Smith BP, Babos M. Sildenafil. [Updated 2022 May 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK558978/
- Galiè N, Ghofrani HA, Torbicki A, Barst RJ, Rubin LJ, Badesch D, Fleming T, Parpia T, Burgess G, Branzi A, Grimminger F, Kurzyna M, Simonneau G; Sildenafil Use in Pulmonary Arterial Hypertension (SUPER) Study Group. Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med. 2005 Nov 17;353(20):2148-57. doi: 10.1056/NEJMoa050010. Erratum in: N Engl J Med. 2006 Jun 1;354(22):2400-1. PMID: 16291984. https://www.nejm.org/doi/full/10.1056/NEJMoa050010
- Sofikitis N, Kaltsas A, Dimitriadis F, Rassweiler J, Grivas N, Zachariou A, Kaponis A, Tsounapi P, Paterakis N, Karagiannis A, Skouros S, Giannakis I, Champilomatis I, Paschopoulos M, Daphnis D, Giakoumakis I, R Gabales M, M Chua JB, Lantin Iii PL, Mamoulakis C, Takenaka A. The Effect of PDE5 Inhibitors on the Male Reproductive Tract. Curr Pharm Des. 2021;27(23):2697-2713. doi: 10.2174/1381612826666200226121510. PMID: 32101115. https://www.eurekaselect.com/article/104866
Disclaimer
HisBlue is not a substitute for professional medical care or advice from your doctor. The health information on the HisBlue website is general and provided for your information only. We have ensured our content is accurate and current, with reviews by expert doctors. However, we cannot guarantee its accuracy or timeliness. This information is not meant to replace the diagnosis, treatment, or judgement of your doctor or another qualified healthcare provider.
Disclaimer
HisBlue is not a substitute for professional medical care or advice from your doctor. The health information on the HisBlue website is general and provided for your information only. We have ensured our content is accurate and current, with reviews by expert doctors. However, we cannot guarantee its accuracy or timeliness. This information is not meant to replace the diagnosis, treatment, or judgement of your doctor or another qualified healthcare provider.
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