Vidalista 40 mg

How Vidalista 40 mg Works

Vidalista 40 mg contains Tadalafil, a phosphodiesterase type (PDE5) inhibitor. It works by relaxing the smooth muscles in the blood vessel walls. This action helps increase blood flow to the penis. It blocks the action of PDE5 and prevents cGMP breakdown. Better cGMP production helps with the contraction and dilation of arteries. 

Tadalafil, present in this pill, increases the cGMP level. So blood can flow easily to the penis. Through increased inflow to the penis, the person has a strong erection. The man will still need sexual stimulation for the medication to work.

Vidalista Uses

Erectile dysfunction (ED) 

Difficulty getting or keeping an erection hard enough for sexual intercourse.

Benign Prostatic Hyperplasia (BPH)  

Prostate gland enlargement that causes painful and frequent urination.

Pulmonary arterial hypertension (PAH) 

Contraction of blood vessels, causing the heart to pump blood harder. This increases BP levels, causing PAH.

Benefits

• Helps to maintain an erection during sex
• Builds sexual confidence 
• Increases relationship satisfaction
• Improves quality of life 

Recommended Dosage

The usual recommended Vidalista dosage is a pill once per day. You can eat normal food while taking a tablet. Take it about 30 minutes to 1 hour before sexual activity. Do take it more than once in 24 hours. Do not crush, chew, split the tablet. Take it as a whole with a full glass of water. 

Missed Dose

This medicine is taken as and when needed before sex. The chances of missing a dose are less for ED. 

For BPH or other conditions, take the missed dose when you remember. If it’s time for the next scheduled dose, skip the missed dose and continue with the next doses as usual.

Overdose

Taking more than the recommended Vidalista 40 dosage can be harmful. If you suspect a tadalafil overdose, get medical attention straight away.

Safety Advice

Alcohol : UNSAFE
It is unsafe to drink alcohol with Vidalista Tadalafil 40mg Tablet.

Pregnancy : SAFE IF PRESCRIBED
Your doctor may prescribe tadalafil if you have severe pulmonary hypertension. Inform your doctor as soon as possible if you are pregnant or trying to get pregnant while under this treatment. However, Vidalista is not meant for women’s sexual health.

Breastfeeding : SEEK YOUR DOCTOR’S ADVICE
No confirmed data is available on the use of tadalafil during breastfeeding. Consult your doctor.

Driving : UNSAFE
This medication can make you dizzy or affect your vision. Do not drive or use hazardous machinery until you have fully understood its effects.

Kidney : CAUTION
Vidalista should not be used in patients with severe kidney problems. If you have mild to moderate kidney problems, consult your healthcare provider.

Liver:  CAUTION
Vidalista 40mg will be processed by your liver, so use caution if you have an existing liver problem. Consult your doctor before using this medication.

Precaution

Before you take this medication, tell your doctor:

1. If you are allergic to tadalafil pills.
2. If you take any medicines containing nitrates. Nitrates are commonly used to treat angina.
3. If you take recreational drugs called “poppers,” like amyl nitrite and butyl nitrite.
4. If you take any medicines called guanylate cyclase stimulators, such as Riociguat.
5. If you have liver disease or kidney disease.
6. If you suffer from diseases such as diabetes, hypertension, etc.
7. If you suffer from any physical deformity of the penis.
8. If you are pregnant or breastfeeding.
9. If you suffer from retinitis pigmentosa.
10. If you have blood cell problems such as sickle cell anemia, multiple myeloma, etc.
11. If you have other medical conditions such as prostate disorder or HIV.
12. If you take other ED medications.

Side effects

Some common Vidalista 40 side effects include:

1. Headache
2. Nausea
3. Back pain
4. Blocked nose
5. Muscle pain
6. Flushed skin
7. Dizziness

Usually, these Tadalafil effects are mild and will go away in time. Severe but rare side effects can include: 

1. Allergic reactions such as hives, breathing difficulty, swelling of face, lips, tongue or throat
2. Sudden loss of vision
3. Sudden loss of hearing
4. Priapism (prolonged erection)
5. Chest pain
6. High BP
7. Low BP
8. Heart attack

Call your doctor if you experience an allergic reaction or unwanted side effects.

Drug interactions

Certain drugs can interact with Vidalista 40 mg (tadalafil tablets) and affect the way it works. Discuss your medical history and current medicines with your healthcare professional to prevent adverse effects. Here are a few medications that can interact with tadalafil tablets:

1. Nitrates (nitroglycerin, isosorbide)
2. Drugs containing amyl or butyl nitrite
3. Alpha blocker medication (doxazosin, tamsulosin, alfuzosin, dutasteride, prazosin, silodosin,terazosin)
4. Azole antifungals (such as itraconazole, ketoconazole, fluconazole, griseofulvin, itraconazole, ketoconazole, and voriconazole) 
5. Macrolide antibiotics (such as clarithromycin and erythromycin)
6. HIV protease inhibitors (such as fosamprenavir, ritonavir, indinavir, nelfinavir, and lovastatin)
7. Hepatitis C virus protease inhibitors (such as boceprevir and telaprevir)
8. Rifampin
9. Riociguat, a drug for pulmonary arterial hypertension
10. Amiodarone 
11. Aprepitant 
12. Bosentan 
13. Carbamazepine
14. Clarithromycin 
15. Diltiazem 
16. Efavirenz 
17. Erythromycin
18. Other medicines for treating erectile dysfunction
19. Phenobarbital 
20. Phenytoin 
21. Rifabutin 
22. Sertraline
23. Telithromycin

Interaction with alcohol

Alcohol can increase the chances of lowering your BP. It can also cause some severe side effects. Avoid consuming alcohol alongside this medication.

Interaction with grapefruit juice

Do not consume grapefruit or grapefruit juice with tadalafil. 

Storage instructions for Vidalista 40

1. Store the medicine in a container. Keep the lid tightly closed.
2. Keep it out of reach of children and pets.
3. Keep the medicine away from heat, moisture, and light.
4. Store it at room temperature.

References:

1. Hatzimouratidis, K. (2014b). A review of the use of tadalafil in the treatment of benign prostatic hyperplasia in men with and without erectile dysfunction. Therapeutic Advances in Urology, 6(4), 135–147. https://doi.org/10.1177/1756287214531639
2. Gong, B., Ma, M., Xie, W., Yang, X., Huang, Y., Sun, T., Luo, Y., & Huang, J. (2017c). Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. International Urology and Nephrology, 49(10), 1731–1740. https://doi.org/10.1007/s11255-017-1644-5
3. Coward, R., & Carson, C. (2008i). Tadalafil in the treatment of erectile dysfunction. Therapeutics and Clinical Risk Management, Volume 4, 1315–1329. https://doi.org/10.2147/tcrm.s3336
4. Young, J. M., Feldman, R. A., Auerbach, S. M., Kaufman, J. M., Garcia, C. S., Shen, W., Murphy, A. M., Beasley, C. M., Hague, J. A., & Ahuja, S. (2005b). Tadalafil improved erectile function at Twenty‐Four and Thirty‐Six hours after dosing in men with erectile dysfunction: US trial. Andrology, 26(3), 310–318. https://doi.org/10.2164/jandrol.04126
5. Shabsigh, R., Broderick, G. A., Althof, S., Natanegara, F., & Wong, D. G. (2009). Daily patterns of sexual intercourse attempts by men with erectile dysfunction treated with tadalafil: influence of age and marital status. International Journal of Impotence Research, 21(5), 285–291. https://doi.org/10.1038/ijir.2009.24