Choosing between Cialis and Viagra for erectile dysfunction (ED) treatment depends on personal preferences and health needs. They work similarly but have different active ingredients and durations of action. Viagra’s active ingredient is Sildenafil Citrate. Cialis’s active ingredient is Tadalafil.
Each medication offers its own benefits and drawbacks. Cialis provides longer-lasting effects, which can enhance spontaneity. Viagra, on the other hand, works well for shorter durations and is ideal for planned activity. Both drugs work by improving blood flow to the penis, but they differ in how long they stay active in the body.
Understanding how these medications affect your body and knowing the differences between them can help you make the best choice for your lifestyle.
Table of Contents
Cialis Vs Viagra: Which One is Better?
Which ED medication is “better” depends on individual needs and preferences. Here are the advantages and disadvantages of using Cialis compared to Viagra for the treatment of erectile dysfunction.
Feature | Cialis (Tadalafil) | Viagra (Sildenafil) |
Duration of Action | Lasts up to 36 hours, allowing more spontaneity. | Lasts 4-6 hours, suitable for shorter periods. |
Effect of Food Intake | Unaffected by food intake, including high-fat meals. | High-fat meals can delay absorption and effectiveness. |
Dosing Options | Offers a daily low-dose option for continuous treatment. | Typically taken on-demand. |
Additional Benefits | Also treats benign prostatic hyperplasia (BPH). | Primarily used for ED. |
Side Effect Duration | Side effects may last longer due to extended presence in the bloodstream. | Side effects are generally shorter due to faster metabolism. |
Unique Side Effects | May cause limb pain, although this is rare. | May cause vision changes, dizziness, skin rash |
Metabolism | Stays in the system longer, which may prolong side effects. | Clears the body faster, which can minimize long-lasting side effects. |
Timing for Use | Does not require precise timing before sexual activity due to long duration. | Needs to be taken closer to anticipated activity, offering less flexibility. |
Consult a doctor to determine the best option based on individual health conditions and potential drug interactions.
What are the key differences in duration of effect between Viagra and Cialis?
Both Viagra and Cialis belong to a group of drugs called PDE5 inhibitors. These drugs help boost the effects of nitric oxide (NO) in your body. During arousal, your body releases nitric oxide. This chemical helps relax the smooth muscle in your penis, which increases blood flow and leads to an erection.
Though both drugs work in similar ways, their active ingredients are different. Viagra uses sildenafil citrate, while Cialis uses tadalafil. These differences affect how long the drugs last in your body.
Viagra, with sildenafil, usually works for 4 to 6 hours. Its effects are short, making it a good choice for occasional or last-minute sexual activity. In some cases, it may work for up to 12 hours, but this is rare.
Cialis, with tadalafil, lasts much longer. It can work for up to 36 hours, which is why it’s called “the weekend pill.” In some cases, the effect may last up to 72 hours, though this is the maximum and not common.
These time frames can vary based on factors like how fast your body processes the drug, the dose, and whether you take it with food.
How do Sildenafil and Tadalafil impact erections?
To understand how Cialis and Viagra work, it’s important to know how an erection normally happens. Here’s a step-by-step breakdown:
- Sexual Stimulation
When a man is sexually aroused, a series of events are initiated.
- Nitric Oxide (NO) Release
Nerves in the penis and the endothelium (lining of blood vessels) release NO.
- Activation of Guanylate Cyclase
NO activates an enzyme called guanylate cyclase.
- Production of Cyclic Guanosine Monophosphate (cGMP)
Guanylate cyclase, in turn, triggers the production of cGMP, a crucial molecule for smooth muscle relaxation.
- Vasodilation and Blood Flow
cGMP promotes the relaxation and widening (vasodilation) of blood vessels in the penis. This allows for increased blood flow into the penis, leading to an erection.
The Role of PDE5 and Its Inhibition
- PDE5: The Erection Spoiler
The erection process is tightly regulated. An enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP, ultimately leading to a decline in erection.
- PDE5 Inhibitors
This is where Cialis (tadalafil) and Viagra (sildenafil citrate) step in. Both are PDE5 inhibitors, meaning they block the action of PDE5.
- Prolonging cGMP’s Effect
These medications block PDE5, allowing cGMP to build up in the smooth muscle cells of your penis. With more cGMP present, the muscles stay relaxed for longer periods. This allows blood to keep flowing into the penis, helping you maintain an erection for a longer time.
Key Points to Remember
- Sexual Stimulation is Essential
Neither Cialis nor Viagra can induce an erection on their own. Sexual stimulation is necessary for initiating the natural release of NO.
- Not “Magic Pills”
These medications don’t increase sexual desire; they merely facilitate the physiological response to arousal.
Cialis and Viagra work by enhancing your body’s natural erection process. They block the PDE5 enzyme, which helps you have a stronger and longer-lasting erection during sexual arousal.
However, it’s important to talk to a healthcare provider first. They can help you decide if these medications are right for you. They will also guide you on the right dosage and explain any possible risks or side effects. This way, you can use the medication safely and get the best results for your needs.
What are the common side effects of Viagra and Cialis?
Both Viagra and Cialis can cause side effects. Since they are both PDE5 inhibitors, they share similar side effects, though some differences exist. Most side effects are mild and often go away over time.
However, if you experience any serious or ongoing side effects, you should seek medical help right away. It’s important to use these medications safely so that you can benefit from them while minimizing risks.
Here’s a breakdown of common side effects:
Shared Side Effects (Viagra and Cialis):
- Headache
Headaches are among the most frequently reported side effects of both medications.
- Flushing
This involves a feeling of warmth or redness in the face, neck, or chest, often accompanied by a flushed appearance.
- Indigestion (Dyspepsia)
This can manifest as heartburn, bloating, nausea, or discomfort in the upper abdomen.
- Nasal Congestion
This can range from a stuffy nose to a runny nose.
- Back Pain
While experienced with both medications, it’s reported more frequently with Cialis.
- Muscle Aches (Myalgia)
Similar to back pain, muscle aches are more commonly associated with Cialis.
- Stomach Upset
This can encompass a range of digestive discomforts, including nausea, diarrhea, and abdominal cramps.
Cialis-Specific Side Effects:
- Myalgia
Tadalafil has been associated with a higher incidence of myalgia (muscle pain) and back pain.
Viagra-Specific Side Effects:
Other than those shared effects, Sildenafil can also cause:
- Vision Changes
These are rare but can include blurred vision, sensitivity to light, or seeing a blue tinge.
- Dizziness
While possible with both medications, dizziness seems to be reported more often with Viagra.
- Rash
Skin rashes are infrequent but possible with Viagra.
Serious Side Effects (Viagra and Cialis):
Although rare, both medications can cause serious side effects, including:
- Priapism
This is a prolonged erection lasting more than four hours, which can be painful and requires immediate medical attention as it can lead to permanent damage.
- Sudden Vision Loss
Seek immediate medical help if you experience any sudden decrease in vision while taking these medications.
- Sudden Hearing Loss or Changes
This can include ear ringing (tinnitus) and requires immediate medical attention.
Everyone responds to medications in different ways, and not everyone will experience side effects. This information is meant for general knowledge and not as medical advice. Always talk to a healthcare provider before using Viagra or Cialis.
Make sure to share any existing health issues and report any side effects you notice. Consulting a doctor helps ensure you take these medications safely and get the most benefit from them.
Describe the relationship between food intake and the effectiveness of both Cialis and Viagra.
There is a notable difference between Cialis and Viagra regarding how food intake affects their effectiveness:
Cialis works just as well with or without food, which makes it easier to take since you don’t need to worry about meals. One of its main benefits is its flexibility in dosing.
Viagra, on the other hand, may be less effective if you eat a heavy or fatty meal. This is because high-fat foods slow down how quickly Viagra gets absorbed into your body. It’s best to take Viagra on an empty stomach for faster and better results.
Hence, Cialis offers more freedom with meals, while Viagra works best when taken without food.. This difference may help you choose the option that fits your lifestyle better.
What are the two main types of dosage options for Cialis and Viagra?
The primary dosage distinction between Viagra and Cialis lies in their frequency of use, influenced by the significant difference in the duration of their effects:
- Viagra (sildenafil)
Viagra is usually taken about an hour before sex. The dose can range from 25mg to 100mg. Some sources suggest daily use of Viagra, but this is not common. It is not as widely recommended as daily use of Cialis. Choosing Viagra allows you to plan your sexual activity better, but you should follow your doctor’s advice on how to use it safely.
- Cialis (tadalafil)
Cialis offers two main dosage options. It can be taken:
- “On-demand”
Similar to Viagra, Cialis can be taken as needed, typically 30 minutes before anticipated sexual activity. The usual starting dose for on-demand use is 10mg. Dosages can be adjusted based on effectiveness and individual tolerance, ranging from 5mg to 20mg.
- Daily
Cialis is unique because it’s also available in lower doses for once-daily use. This option provides continuous treatment for ED, allowing for more spontaneous sexual activity without having to time medication intake. The typical starting dose for daily use is 2.5mg, which can be increased to 5mg if needed.
The choice between “as-needed” and “daily” dosing depends on your needs. It also varies based on how often you have sex and any health issues you may have. Your tolerance to medication matters, too.
It’s important to talk to a healthcare professional. They can help you find the best dosage plan for you. This ensures you get the most benefit while using the medication safely.
What factors are considered when determining the appropriate dosage for Cialis and Viagra?
Here are the factors to consider when determining the appropriate dosage for Cialis and Viagra:
- Individual Needs and Preferences
The choice of medication and dosage depends on individual factors such as how often a person has sex, the desired duration of effect, and personal preferences. For instance, Cialis might be more suitable for someone who has sex frequently or prefers spontaneity due to its longer duration of effect, while Viagra might be a better fit for someone seeking short-term relief for occasional use.
- Severity of ED
The dosage of both Viagra and Cialis can be adjusted based on the severity of ED. Higher doses may be prescribed for more severe cases. For example, the typical starting dose of Cialis is 10 mg, but it can be increased to 20 mg if the lower dose is ineffective. For Viagra, the typical starting dose is 50 mg, which can be increased to 100 mg if needed.
- Age
Age is generally a factor considered when determining the dosage for many medications, including ED medications. For instance, the elderly (over 65 years of age) may be started on a lower dose of Viagra (25 mg).
- Metabolism
A person’s metabolism can influence how quickly their body processes and eliminates a drug. While not directly addressed in the sources for Viagra and Cialis, a faster metabolism might necessitate a higher dosage or more frequent dosing, while a slower metabolism might require a lower dosage to avoid potential side effects.
- Presence of Other Health Conditions
The presence of certain health conditions, such as liver or kidney problems, may necessitate dosage adjustments for Cialis. For both Viagra and Cialis, cardiovascular issues like high blood pressure or a history of heart disease require caution, and in some cases, these medications might be deemed unsafe.
- Drug Interactions
Both medications can interact with certain drugs and substances, potentially requiring dosage adjustments or even prohibiting their use altogether. For instance, using Viagra or Cialis with nitrates (often prescribed for chest pain or heart conditions) can lead to a dangerous drop in blood pressure. It is crucial to inform your healthcare provider about all medications and supplements you are taking, including over-the-counter drugs and recreational substances, to avoid potentially harmful interactions.
- Side Effects
Dosage adjustments might be necessary if a person experiences intolerable side effects. For example, if a person experiences severe headaches or indigestion while taking Cialis, the dosage may be reduced.
It’s crucial to consult with a healthcare professional to determine the safest and most appropriate dosage for either Cialis or Viagra. They can assess individual health conditions, consider potential drug interactions, and recommend the best course of treatment. Never self-medicate or adjust your dosage without consulting your doctor.
The Final Thought
Ultimately, the choice between Cialis and Viagra comes down to what works best for you. Cialis offers a longer window of effectiveness, which may be ideal for those who want more flexibility. Viagra, with its shorter duration, might suit those looking for a quick, reliable option for specific moments. Both medications can enhance your experience, but it’s essential to consider factors like side effects, timing, and your overall health. Speak with your doctor to find the best option tailored to your needs. Making an informed decision ensures you get the most out of your treatment while staying safe.
Frequently Asked Questions
Does Cialis get you harder than Viagra?
Both Cialis and Viagra help you get and keep an erection. However, neither is proven to make you “harder” than the other. They both work by boosting blood flow to the penis during arousal.
What is the best pill to stay hard longer?
Cialis lasts up to 36 hours, which makes it the better option if you want a longer window of effectiveness. Viagra lasts about 4-6 hours, offering a shorter duration.
Who should not take Viagra or Cialis?
People taking nitrates for heart problems should avoid Viagra and Cialis. Those with serious heart, liver, or kidney issues should also talk to a doctor before using these drugs.
Which is better, Viagra or Cialis?
Cialis offers a longer duration, while Viagra works well for shorter, planned activity. The “better” option depends on your needs and lifestyle.
Do men prefer Viagra or Cialis?
Some men prefer Cialis for its longer effect, while others choose Viagra for its quick, short-term benefits. It depends on personal preference.
Which is more powerful, Viagra or tadalafil?
Both Viagra and tadalafil (Cialis) are equally effective at treating ED. The key difference is how long they last, not their strength.
References
- Gong, B., Ma, M., Xie, W. et al. Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. Int Urol Nephrol 49, 1731–1740 (2017). https://doi.org/10.1007/s11255-017-1644-5
- Ali ST. Effectiveness of sildenafil citrate (Viagra) and tadalafil (Cialis) on sexual responses in Saudi men with erectile dysfunction in routine clinical practice. Pak J Pharm Sci. 2008 Jul;21(3):275-81. PMID: 18614424. https://pubmed.ncbi.nlm.nih.gov/18614424/
- Panchatsharam PK, Durland J, Zito PM. Physiology, Erection. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK513278/
- Dhaliwal A, Gupta M. PDE5 Inhibitors. [Updated 2023 Apr 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK549843/
- Smith BP, Babos M. Sildenafil. [Updated 2023 Feb 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK558978/
- Nichols DJ, Muirhead GJ, Harness JA. Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality. Br J Clin Pharmacol. 2002;53 Suppl 1(Suppl 1):5S-12S. doi: 10.1046/j.0306-5251.2001.00027.x. PMID: 11879254; PMCID: PMC1874258. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874258/
- Deyoung L, Chung E, Kovac JR, Romano W, Brock GB. Daily use of sildenafil improves endothelial function in men with type 2 diabetes. J Androl. 2012 Mar-Apr;33(2):176-80. doi: 10.2164/jandrol.111.013367. Epub 2011 Jun 16. PMID: 21680809. https://pubmed.ncbi.nlm.nih.gov/21680809/#:~:text=At%20the%20conclusion%20of%20the,01).
Disclaimer
HisBlue is not a substitute for professional medical care or advice from your doctor. The health information on the HisBlue website is general and provided for your information only. We have ensured our content is accurate and current, with reviews by expert doctors. However, we cannot guarantee its accuracy or timeliness. This information is not meant to replace the diagnosis, treatment, or judgement of your doctor or another qualified healthcare provider.