Zenegra 100mg (sildenafil)

Zenegra 100mg is a prescription medicine available in tablet form. It is primarily used for the treatment of erectile dysfunction in men. The active ingredient in this tablet is sildenafil. It belongs to the group of medicines called PDE5 inhibitors. It works by improving blood flow to the penis. This helps men to get or maintain a hard, erect penis suitable for sexual intercourse. Zenegra 100mg works only in the presence of a sexual stimulus.

$60.00$420.00

Treats Depression, Panic disorder, Anxiety disorder
Quantity 10 tablets per strip
Contains Paroxetine
Lasts 17 to 22 hours
Manufactured By Consern Pharma Limited

How does it Work?

Zenegra 100mg contains the active ingredient sildenafil. It belongs to a group of medicines, PDE5 inhibitors.

During sexual arousal, a molecule called nitric oxide (NO) is released within the penis. This increases levels of another molecule called the cGMP. cGMP causes the smooth muscles inside the penis to relax.

As a result, the blood vessels open wider, allowing blood flow. It causes the corpus cavernosum (the spongy tissue in the penis) to swell. Thus, the penis becomes larger and stiff enough for sexual intercourse.

However, an enzyme called PDE5 breaks down cGMP molecules, ending the erection. PDE5 inhibitors such as sildenafil stop PDE5 from working too quickly and prevent the cGMP breakdown. Hence, the action of nitric oxide is enhanced, promoting blood flow. This helps prolong the erection, making it firm enough for intercourse.   

Note that Zenegra 100mg itself directly does not cause an erection. It helps the body respond better to sexual arousal. Sildenafil has no effect where sexual stimulation is absent.

Uses

  • Erectile Dysfunction (ED):

Difficulty getting or keeping an erection firm enough to have sex. The condition is also known as ‘impotence’. It prevents some men from having a pleasant sexual performance.

  • Pulmonary Arterial Hypertension (PAH):

A type of high blood pressure in the arteries that carry blood to the lungs.

Recommended Dose

For erectile dysfunction, take one Zenegra 100mg about 1 hour before sex. Have it orally with a glass of water. Do not take more than the recommended dose in 24 hours.

A lower dose of sildenafil may be prescribed for first-time users to minimize the risk of unpleasant effects.

For pulmonary hypertension, please take it as prescribed by your doctor.

Missed Dose

For erectile dysfunction, Zenegra 100mg is taken as needed before sex. There is little chance of missing out on a dose in that case.

If you forget to take a prescribed dose, take it as soon as you remember. If it is about time for your next scheduled dose, just leave out the missed dose. Then, keep taking the next doses as usual.

Overdose

Zenegra 100mg tablets need to be taken at the right dosage. Only then can it produce the desired results. Taking too much ED medication can lead to serious side effects. Talk to your doctor if there is an overdose. Or if you’re worried about the side effects listed below.

Side Effects

Here are some possible side effects of Zenegra 100mg tablets:

  • headache
  • heartburn
  • nausea
  • flushing
  • dizziness
  • diarrhea
  • nosebleeds
  • numbness
  • muscle pain
  • nasal congestion

In rare cases, sildenafil can lead to:

  • sudden loss of vision
  • blurred vision
  • loss of hearing
  • ringing in ears
  • chest pain
  • difficulty in breathing
  • painful erection that lasts longer than 4 hours

Safety Advice

  • Zenegra 100mg tablets are generally safe when taken as prescribed.
  • Let your doctor know if you have the following:
  1. heart disease
  2. stroke
  3. low blood pressure
  4. liver or kidney problems
  5. bleeding disorder
  6. or any other conditions
  • Do not take Zenegra tablets if you are intolerant to sildenafil or if you are taking nitrates for chest pain or heart problems.
  • Learn about potential drug interactions, including the ones listed above.
  • Call your doctor if any side effects bother you.
  • Zenegra may make you feel drowsy or affect your vision. Do not drive or operate hazardous machinery under its influence.
  • Women and children should not use this medicine.  
  • Zenegra 100mg should not be taken more than once a day.

Medical Interactions

Zenegra 100mg tablets may interact with certain other medications. This may change the way this drug works and increase the risk of side effects. Tell your pharmacist or doctor if you are taking:

  • prescription drugs
  • over-the-counter (OTC) medications
  • vitamins
  • herbs or any other supplement

The following drugs tend to have more severe interactions with sildenafil:

  • nitrates (taken for chest pain)
  • alpha-blockers (treat high blood pressure or hypertension)
  • antifungals (such as itraconazole, ketoconazole)
  • blood thinners such as warfarin
  • barbiturates (treat improving sleep, reducing anxiety, muscle spasms)
  • beta-blockers such as atenolol or carvedilol
  • some antibiotics
  • HIV protease inhibitors (used to treat viral infections)
  • other ED medicines
  • medicines for seizures

Storage

  • Zenegra tablets should be stored at room temperature.
  • The medicine should not be left in warm or humid places. Do not store it in the bathroom cabinet or near a sink. Heat, air, and steam can spoil the medicine.
  • Do not repack the medicine. Store it in the original packaging until you consume it.
  • Place the medicines in a locked cabinet where children and pets cannot reach.
  • Do not take expired medicines. Even if you bought them recently, check the label. If you’ve taken expired medicines by mistake, inform your doctor.
  • Discard any pills that have gone past their expiry date. Follow your local regulations and laws for their safe disposal.

Refrences

  1. Fink HA, Mac Donald R, Rutks IR, Nelson DB, Wilt TJ. Sildenafil for male erectile dysfunction: a systematic review and meta-analysis. Arch Intern Med. 2002 Jun 24;162(12):1349-60. doi: 10.1001/archinte.162.12.1349. PMID: 12076233. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/211714
  2. Loran OB, Ströberg P, Lee SW, Park NC, Kim SW, Tseng LJ, Collins S, Stecher VJ. Sildenafil citrate 100 mg starting dose in men with erectile dysfunction in an international, double-blind, placebo-controlled study: effect on the sexual experience and reducing feelings of anxiety about the next intercourse attempt. J Sex Med. 2009 Oct;6(10):2826-35. doi: 10.1111/j.1743-6109.2009.01428.x. PMID: 19817982. https://www.jsm.jsexmed.org/article/S1743-6095(15)32273-6/fulltext
  3. Smith BP, Babos M. Sildenafil. [Updated 2022 May 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK558978/
  4. Galiè N, Ghofrani HA, Torbicki A, Barst RJ, Rubin LJ, Badesch D, Fleming T, Parpia T, Burgess G, Branzi A, Grimminger F, Kurzyna M, Simonneau G; Sildenafil Use in Pulmonary Arterial Hypertension (SUPER) Study Group. Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med. 2005 Nov 17;353(20):2148-57. doi: 10.1056/NEJMoa050010. Erratum in: N Engl J Med. 2006 Jun 1;354(22):2400-1. PMID: 16291984. https://www.nejm.org/doi/full/10.1056/NEJMoa050010
  5. Sofikitis N, Kaltsas A, Dimitriadis F, Rassweiler J, Grivas N, Zachariou A, Kaponis A, Tsounapi P, Paterakis N, Karagiannis A, Skouros S, Giannakis I, Champilomatis I, Paschopoulos M, Daphnis D, Giakoumakis I, R Gabales M, M Chua JB, Lantin Iii PL, Mamoulakis C, Takenaka A. The Effect of PDE5 Inhibitors on the Male Reproductive Tract. Curr Pharm Des. 2021;27(23):2697-2713. doi: 10.2174/1381612826666200226121510. PMID: 32101115. https://www.eurekaselect.com/article/104866
  6. Kim JN, Oh JJ, Park DS, Hong YK, Yu YD. Influence of Alcohol on Phosphodiesterase 5 inhibitors Use in Middle- to Old-Aged Men: A Comparative Study of Adverse Events. Sex Med. 2019 Dec;7(4):425-432. doi: 10.1016/j.esxm.2019.07.004. Epub 2019 Aug 20. PMID: 31444051; PMCID:

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HisBlue is not a substitute for professional medical care or advice from your doctor. The health information on the HisBlue website is general and provided for your information only. We have ensured our content is accurate and current, with reviews by expert doctors. However, we cannot guarantee its accuracy or timeliness. This information is not meant to replace the diagnosis, treatment, or judgement of your doctor or another qualified healthcare provider.

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Frequently Asked Questions (FAQs)

Ans. Zenegra 100mg typically takes 30-60 minutes to become active and usually reaches peak effects within 2 hours.
Ans. Zenegra 100mg may interact with certain medications, especially nitrates, leading to adverse effects or reduced efficacy. Always consult your doctor before taking it with other medications.
Ans. Common side effects include headache, muscle pain, diarrhea, flushing, dizziness, and stomach upset. These are usually temporary, but if they are severe or persistent, contact your doctor.
Ans. Zenegra 100mg is intended for men with erectile dysfunction (ED) and is not designed for use by women. It is unlikely to affect a partner's pregnancy or breastfeeding.

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Zenegra 100mg (sildenafil)
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