Forzest 20 mg

Side Effects

Common side effects of Forzest 20mg (tadalafil) are:

• headache
• indigestion
• diarrhoea
• flushing
• muscle pain
• heartburn
• nausea
• cough

In rare cases, tadalafil can cause:

• loss of vision
• blurred vision
• changes in colour vision
• painful erection that lasts longer than 4 hours
• loss of hearing
• ringing in ears
• dizziness
• chest pain

Important Advisory

• Take Forzest 20mg as prescribed.
• Do not take this drug if you are allergic to tadalafil.
• Read the label. Check all information carefully before starting the medicine.
• Generic Forzest 20mg is generally safe as a single, one-time dose. For long-term use, consult your healthcare provider. Ask them if you have questions about any possible drug interactions.
• To make sure Forzest is safe for you, inform your doctor if you have the following:
  • heart problems
  • a heart attack or stroke
  • angina (chest pain)
  • high or low blood pressure
  • lungs problems
  • liver or kidney disease
  • bleeding disorder
  • or any other health conditions
• Forzest 20mg may make you feel dizzy and lightheaded. Do not drive or operate heavy machinery while under its influence.
• Alcohol may impair your ability to get an erection. So, if you’re taking this medicine for ED, do not drink a lot of alcohol.
• Do not have it with grapefruit juice.
• Forzest 20mg is not meant to be used by women or children.
• If you see any side effects that worsen over time, call your doctor.

Medical Interactions

Some medications may interact with Forzest 20mg. An interaction can occur because sometimes two substances do not work well together.

Drug interactions can make Forzest 20mg less effective. Or it can increase the risk of side effects. Interactions are also possible with certain health conditions. Discuss with your doctor if you are taking any:

• prescription drugs
• over-the-counter (OTC) medications
• vitamins
• herbs or any other supplement

Potential drug interactions with Forzest 20mg may include:

• nitrates or diltiazem (those given for angina)
• alpha-blockers (i.e., treat hypertension)
• some antifungals like fluconazole
• aprepitant (treats nausea and vomiting)
• bosentan (or other drugs for high blood pressure)
• carbamazepine (relieves nerve pain)
• antibiotic such as rifabutin or rifampin
• efavirenz (treats and prevents HIV/AIDS)
• HIV protease inhibitors
• anxiety-relieving medicines such as phenobarbital
• antidepressant medicines such as sertraline
• other medications for erectile dysfunction
• other medications for PAH

Storage Instructions

• Store Forzest 20mg at room temperature.
• Keep the tablets in their original packaging. Do not keep in the same vial with other medicines.
• Store it in a dark, cool, dry place (e.g., a dresser drawer). Keep away from the bathroom, sink or any hot appliances.
• Keep out of the reach of children and pets.
• Check the expiry date printed on the package or label before using it. Do not store or use expired or unwanted medicines. Safely dispose of them following your local drug disposal guidelines.

References

1. Coward RM, Carson CC. Tadalafil in the treatment of erectile dysfunction. Ther Clin Risk Manag. 2008 Dec;4(6):1315-30. doi: 10.2147/tcrm.s3336. PMID: 19337438; PMCID: PMC2643112. https://www.dovepress.com/tadalafil-in-the-treatment-of-erectile-dysfunction-peer-reviewed-fulltext-article-TCRM 
2. Hatzimouratidis K. A review of the use of tadalafil in the treatment of benign prostatic hyperplasia in men with and without erectile dysfunction. Ther Adv Urol. 2014 Aug;6(4):135-47. doi: 10.1177/1756287214531639. PMID: 25083163; PMCID: PMC4054509. https://journals.sagepub.com/doi/10.1177/1756287214531639 
3. Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang J. Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. Int Urol Nephrol. 2017 Oct;49(10):1731-1740. doi: 10.1007/s11255-017-1644-5. Epub 2017 Jul 24. PMID: 28741090; PMCID: PMC5603624.https://link.springer.com/article/10.1007/s11255-017-1644-5 
4. Frajese GV, Pozzi F, Frajese G. Tadalafil in the treatment of erectile dysfunction; an overview of the clinical evidence. Clin Interv Aging. 2006;1(4):439-49. doi: 10.2147/ciia.2006.1.4.439. PMID: 18046921; PMCID: PMC2699638. https://www.atypon-link.com/DMP/doi/abs/10.2147/ciia.2006.1.4.439 
5. Wang Y, Bao Y, Liu J, Duan L, Cui Y. Tadalafil 5 mg Once Daily Improves Lower Urinary Tract Symptoms and Erectile Dysfunction: A Systematic Review and Meta-analysis. Low Urin Tract Symptoms. 2018 Jan;10(1):84-92. doi: 10.1111/luts.12144. Epub 2016 Nov 5. PMID: 29341503 https://onlinelibrary.wiley.com/doi/10.1111/luts.12144
6. Sofikitis N, Kaltsas A, Dimitriadis F, Rassweiler J, Grivas N, Zachariou A, Kaponis A, Tsounapi P, Paterakis N, Karagiannis A, Skouros S, Giannakis I, Champilomatis I, Paschopoulos M, Daphnis D, Giakoumakis I, R Gabales M, M Chua JB, Lantin Iii PL, Mamoulakis C, Takenaka A. The Effect of PDE5 Inhibitors on the Male Reproductive Tract. Curr Pharm Des. 2021;27(23):2697-2713. doi: 10.2174/1381612826666200226121510. PMID: 32101115https://www.eurekaselect.com/article/104866