Treats | Moderate to severe pain |
Quantity | 10 tablets per strip |
Active Ingredient | Tapentadol |
Lasts | Up to 4 hours |
Manufactured By | Zuventus Healthcare Ltd |
How does it Work?
Tapentadol is an active ingredient in Tapenta 100 mg. It is a synthetic analgesic that acts centrally. It’s believed to work through two main mechanisms, although their clinical relevance is not entirely clear. Tapentadol acts as a selective mu-opioid receptor (MOR) agonist. It binds to MOR with greater affinity than delta—and kappa-opioid receptors. Additionally, Tapentadol inhibits noradrenaline reuptake. This action increases noradrenaline levels and activates alpha-2 receptors, promoting analgesia. While Tapentadol is also a weak serotonin reuptake inhibitor, this aspect does not contribute to its analgesic effect.
Uses
Recommended Dose
Side Effects
While using Tapenta 100 mg, be mindful of potential side effects that may arise. These include:
- headache
- heartburn
- stomach pain
- dry mouth
- excessive tiredness
- anxiety
- drowsiness
- difficulty falling asleep or staying asleep
- abnormal dreams
- irritability
- sudden feeling of warmth
Serious effects:
- seizures
- agitation, hallucinations (seeing things or hearing voices that do not exist), fever, sweating, confusion, fast heartbeat, shivering, severe muscle stiffness or twitching, loss of coordination, nausea, vomiting, or diarrhea
- nausea, vomiting, loss of appetite, weakness, or dizziness
- inability to get or keep an erection
- irregular menstruation
- decreased sexual desire
- rash
- itching
- hives
- swelling of the eyes, face, lips, tongue, or throat
- hoarseness
- difficulty breathing or swallowing
- chest pain
- feeling lightheaded when you change positions
- feeling faint
- loss of consciousness
- feeling overheated
- heavy sweating
- worsening pain, increased sensitivity to pain, or new pain, especially after taking tapentadol
If you experience any severe or persistent side effects or notice any changes in your health, consult your doctor immediately.
Safety Advice
You should not consume Tapenta 100 mg if you have or have had a history of:
- Allergic to Tapentadol
- Angioedema
- Hypersensitivity
- Depression
- mood problems
- suicidal thoughts or behavior
- street drugs consumption
- Alcohol consumption
- kidney problems
- heart problems
- bleeding issues
- low blood platelet count
Medical Interactions
Tapenta 100 mg may interact with other drugs, leading to side effects. Tell your doctor if you take any of the following:
- benzodiazepines, such as alprazolam (Xanax) or diazepam (Valium).
- other narcotic pain medications
- muscle relaxants
- sedatives
- sleeping pills.
- medications for mental illness or nausea
- tranquilizers
Inform your healthcare provider about all medicines you take, including prescriptions, over-the-counter drugs, vitamins, or herbal supplements. We also suggest you to avoid drinking alcohol. Alcohol can increase the risk of side effects such as sleepiness and dizziness.
Storage
- Keep your medications in their original containers or packaging.
- Store them in a cool, dry place away from sunlight and moisture.
- Make sure they’re out of reach of children and pets.
- Check the expiration dates regularly and throw away any expired or unused medications.
References
- Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 547. https://pharmacomedicale.org/images/cnpm/CNPM_2016/katzung-pharmacology.pdf
- Tapentadol. Gurabo, PR: Janssen Ortho, LLC; 2008 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022304s014s015lbl.pdf
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) https://cdscoonline.gov.in/CDSCO/Drugs
- Tapentadol [Prescribing Information]. Stoughton, MA: Collegium Pharmaceutical, Inc.; 2023. [Accessed 20 Feb. 2024] (online) https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/022304s024lbl.pdf
Disclaimer
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