Estrofem 2 mg

How Estrofem 2 mg works

Estrofem is somewhat similar to the naturally produced human estrogen in terms of chemical and biological composition. Estrofem 2 mg works by restoring the estrogen level in the body. By restoring plasma estrogen, it reduces the symptoms of estrogen deficiency. Estrofem aids menopausal women by suppressing gonadotropin secretion. 

The benefits of the treatment should start a few months after you started taking Estrofem. The first few weeks of using hormone replacement therapy can include slight bleeding or spotting. The treatment can also be stopped at any time, although it is better to consult your physician before ceasing treatment. 

Uses of Estrofem 2 mg

Estrofem 2 mg tablets are used to deal with the symptoms of menopause that can lead to hot flushes in the:

1. Chest
2. Neck
3. Face

Other than menopause, Estrofem may be recommended by a physician to treat symptoms of:

1. Vaginal atrophy 
2. Prostate cancer
3. Osteoporosis

Dosage

Estrofem 2 mg tablets should be taken once a day, at the same time each day if possible. Each tablet should be swallowed directly, with or without water. If the patient is not on any other form of HRT, this tablet can be taken at any time that is convenient. It is recommended that the patient consults their physician before starting HRT. If the patient has had a hysterectomy then they may start the treatment immediately as well. In case the bleeding hasn’t stopped, wait for a week before starting treatment. 

Overdose:

Estrofem overdose can lead to a few symptoms such as:

1. Excessive vaginal bleeding
2. Drowsiness or fatigue
3. Tenderness in breasts or breast lumps
4. Blood clots or risk of stroke
5. Severe weight changes

Side effects of Estrofem 2 mg

Different side effects may be experienced when using Estrofem 2 mg, although the common ones are generally rare. Some of these are:

1. Headache
2. Difficulty sleeping
3. Anxiousness or feelings of nervousness
4. Dizziness
5. Gastrointestinal problems
6. Toothache
7. Back pain

Important Advisory

There are certain situations where consumption of Estrofem is prohibited. It is important to discuss your medical history with your physician beforehand, to prevent any complications during treatment. The tablet should not be used in the following cases:

1. Patients who have had breast cancer or any form of cancer that is sensitive to estrogen.
2. Estrofem may also increase blood pressure or the risk of blood clots, benign tumors, dementia, and endometrial cancer. The dosage of the medicine should be reduced in case the patient has liver problems or is breastfeeding. 
3. Patients with any case of undetected vaginal bleeding, excessive thickness in the womb lining that has been left untreated.
4. Patients with blood clots such as in legs or lungs, blood clotting disorders such as protein C deficiency, or any disease that was a result of a blood clot formed in the arteries such as a stroke or heart attack.
5. Any patient who has a history of liver disease, or with a liver not functioning normally, must avoid Estrofem.
6. Anyone with a hereditary blood disorder known as porphyria must also not use this treatment. 
7. Patients who are allergic to estradiol or any ingredient found in Estrofem must refrain from using this medication.

Interactions with Other Drugs

Estrofem may interact with certain compounds or ingredients that the patient is consuming, leading to unwanted results. To prevent this, inform your physician about all the medications that you are currently using, and be sure to avoid substances that may interact with Estrofem. 

Levothyroxine interacts with Estrofem and if you need to take both medications at the same time, your physician must be informed beforehand. Any vitamins or supplements that you are taking must also be approved by a health official. 

Storage Instructions

1. Keep the tablets out of reach from children.
2. Keep the tablets in a cool and dry place, preferably below 25℃.
3. Do not place it in a refrigerator.
4. Dispose of the medicine carefully, with instructions from a pharmacist.

Frequently Asked Questions (FAQs)

Q1. Can I take an Estrofem 2 mg tablet with food? 

Ans: The medicine can be taken with or without food and drink. It is recommended that the tablet be swallowed with a glass of water.

Q2. Can Estrofem prevent pregnancy?

Ans: Estrofem is not a birth control pill or a contraceptive of any sort. It is taken only after women show signs of estrogen deficiency as a result of a hysterectomy. After a hysterectomy, it is not possible to get pregnant. 

 

Q3. What alternatives are available for patients who cannot use Estrofem? 

Ans: Your doctor may recommend several lifestyle changes such as exercise or diet-related changes to replace medication. These changes may also help deal with the symptoms. There are also medications other than hormone therapy that can replace HRT.

Q4. When is the ideal time to try hormone therapy? 

Ans: Estrofem is for women who are going through menopause, and as such, age is an important fact to consider before opting for HRT. Your physician first makes sure that no other health risks or aspects of your past medical history will interfere with the treatment or have a negative effect. 

 

References:

1. https://pubmed.ncbi.nlm.nih.gov/13678382/
2. https://pubchem.ncbi.nlm.nih.gov/compound/Estrofem
3. https://www.ncbi.nlm.nih.gov/books/NBK538260/
4. https://www.ncbi.nlm.nih.gov/books/NBK549797/